動詞 estrange:

1. remove from customary environment or associations
2. arouse hostility or indifference in where there had formerly been love, affection, or friendliness
   同義詞：alienate, alien, disaffect

1. His behaviour estrange him from his brother.
   他的行為使他與哥哥疏遠(yuǎn)了。
2. They are estranged.
   他們疏遠(yuǎn)了。
3. He is estranged from his wife.
   他和妻子分居了。

es.trange

v.tr.（及物動詞）
es.tranged,es.trang.ing,es.trang.es
To make hostile, unsympathetic, or indifferent; alienate.
使疏遠(yuǎn)：使懷有敵意，使不友善或使疏遠(yuǎn)；離間
To remove from an accustomed place or set of associations.
使分離：使離開熟悉的環(huán)境或親友等

來源：
Middle English estraungen
中古英語 estraungen
from Old French estrangier
源自 古法語 estrangier
from Latin extr3ne3re [to treat as a stranger, disown]
源自 拉丁語 extr3ne3re [像對陌生人一樣對待，否認(rèn)與自己有關(guān)系]
from extr3neus [foreign] * see strange
源自 extr3neus [外國的，不相干的] *參見 strange

【引伸】
estrange.ment
n.（名詞）
estrang.er
n.（名詞）
<參考詞匯><同義詞>estrange,alienate,disaffectThese verbs refer to disruption of a bond of love, friendship, or loyalty.Estrange and alienate are often used with reference to two persons, such as a husband and wife, whose harmonious relationship has been replaced by hostility or indifference:
這些動詞是指對愛情、友誼和忠實(shí)的背叛。Estrange 和 alienate 經(jīng)常被用于兩個(gè)人的時(shí)候， 例如丈夫與妻子的合諧、融洽關(guān)系已經(jīng)被敵意和分歧替代：
例句：
Political disagreements led to quarrels that finally estranged the two friends.
政治上的不同觀點(diǎn)使兩個(gè)朋友爭執(zhí)，最后終于導(dǎo)致破裂；

例句：
His persistent antagonism caused his wife to be alienated from him.
固執(zhí)的對立終于使得妻子疏遠(yuǎn)了他。

Disaffect usually implies discontent, ill will, and disloyalty within the membership of a group:
Disaffect 通常暗指一群成員的不滿、惡意和不忠：
例句：
Colonists were disaffected by the autocratic actions of the royal governor.
殖民地居民對皇家總督的暴虐行為極為不滿